From the general Boston direction take Route 95 North.
On the Maine side, take exit #25 (formerly #3) to Kennebunk/Kennebunkport on Route 35.

After passing through downtown Kennebunk continue to follow Route 35 to Kennebunkport by:

Turning left at the first traffic light

Turn right at the second traffic light (immediately after the first)

You are now on Summer Street. After approximately 1.0 mile, you will see the "Wedding Cake House" on the left side.